3cjo
From Proteopedia
Crystal structure of KSP in complex with inhibitor 30
Template:ABSTRACT PUBMED 18578472
About this Structure
3CJO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2- (hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer., Cox CD, Coleman PJ, Breslin MJ, Whitman DB, Garbaccio RM, Fraley ME, Buser CA, Walsh ES, Hamilton K, Schaber MD, Lobell RB, Tao W, Davide JP, Diehl RE, Abrams MT, South VJ, Huber HE, Torrent M, Prueksaritanont T, Li C, Slaughter DE, Mahan E, Fernandez-Metzler C, Yan Y, Kuo LC, Kohl NE, Hartman GD, J Med Chem. 2008 Jun 25;. PMID:18578472
Page seeded by OCA on Wed Jul 9 10:10:45 2008
