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3d20
From Proteopedia
Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA
Template:ABSTRACT PUBMED 18597780
About this Structure
3D20 is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir., Liu F, Kovalevsky AY, Tie Y, Ghosh AK, Harrison RW, Weber IT, J Mol Biol. 2008 Aug 1;381(1):102-15. Epub 2008 Jul 1. PMID:18597780
Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114., Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136
Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S., Liu F, Boross PI, Wang YF, Tozser J, Louis JM, Harrison RW, Weber IT, J Mol Biol. 2005 Dec 9;354(4):789-800. Epub 2005 Oct 21. PMID:16277992
Page seeded by OCA on Wed Jul 16 08:56:04 2008
Categories: HIV-1 retropepsin | Human immunodeficiency virus 1 | Single protein | Ghosh, A K. | Harrison, R W. | Kovalesky, A Y. | Liu, F. | Tie, Y. | Weber, I T. | Aid | Aspartyl protease | Capsid maturation | Capsid protein | Cytoplasm | Dna integration | Dna recombination | Dna-directed dna polymerase | Drug resistance | Endonuclease | Flap mutant | Hiv-1 | Hydrolase | I54v | Lipoprotein | Magnesium | Membrane | Metal-binding | Multifunctional enzyme | Myristate | Nuclease | Nucleotidyltransferase | Nucleus | Phosphoprotein | Protease | Ribosomal frameshifting | Rna-binding | Rna-directed dna polymerase | Transferase | Viral nucleoprotein | Virion | Zinc | Zinc-finger
