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2ghm

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Template:STRUCTURE 2ghm

Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-895449

Template:ABSTRACT PUBMED 16632356

About this Structure

2GHM is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1., Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ, Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:16632356

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