1k4h

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Image:1k4h.jpg

1k4h, resolution 1.80Å

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CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH 2,6-Diamino-8-propylsulfanylmethyl-3H-quinazoline-4-one

About this Structure

1K4H is a Single protein structure of sequence from Zymomonas mobilis with ZN and APQ as ligands. Active as Queuine tRNA-ribosyltransferase, with EC number 2.4.2.29 Full crystallographic information is available from OCA.

Reference

De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity., Meyer EA, Brenk R, Castellano RK, Furler M, Klebe G, Diederich F, Chembiochem. 2002 Mar 1;3(2-3):250-3. PMID:11921407

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