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2nnx

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Revision as of 12:33, 27 July 2008 by OCA (Talk | contribs)
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Image:2nnx.png

Template:STRUCTURE 2nnx

Contents

Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase

Template:ABSTRACT PUBMED 17092942

Disease

Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[147450]

About this Structure

2NNX is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability., Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR, J Biol Chem. 2007 Jan 5;282(1):345-52. Epub 2006 Nov 8. PMID:17092942

Page seeded by OCA on Sun Jul 27 15:33:46 2008

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