2rfs
From Proteopedia
Contents |
X-ray structure of SU11274 bound to c-Met
Template:ABSTRACT PUBMED 18055465
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
2RFS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations., Bellon SF, Kaplan-Lefko P, Yang Y, Zhang Y, Moriguchi J, Rex K, Johnson CW, Rose PE, Long AM, O'Connor AB, Gu Y, Coxon A, Kim TS, Tasker A, Burgess TL, Dussault I, J Biol Chem. 2008 Feb 1;283(5):2675-83. Epub 2007 Nov 30. PMID:18055465
Page seeded by OCA on Sun Jul 27 16:02:51 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Bellon, S F. | Dussault, I. | Kaplan-Lefko, P. | Moriguchi, J. | Yang, Y. | Zhang, Y. | Atp-binding | C-met | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Proto-oncogene | Receptor tyrosine kinase | Su11274 | Transferase | Transmembrane | Tyrosine-protein kinase