3cbh
From Proteopedia
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THREE-DIMENSIONAL STRUCTURE OF CELLOBIOHYDROLASE FROM TRICHODERMA REESEI
Overview
The enzymatic degradation of cellulose is an important process, both, ecologically and commercially. The three-dimensional structure of a, cellulase, the enzymatic core of CBHII from the fungus Trichoderma reesei, reveals an alpha-beta protein with a fold similar to but different from, the widely occurring barrel topology first observed in triose phosphate, isomerase. The active site of CBHII is located at the carboxyl-terminal, end of a parallel beta barrel, in an enclosed tunnel through which the, cellulose threads. Two aspartic acid residues, located in the center of, the tunnel are the probable catalytic residues.
About this Structure
3CBH is a Single protein structure of sequence from Hypocrea jecorina. Active as Cellulose 1,4-beta-cellobiosidase, with EC number 3.2.1.91 Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of cellobiohydrolase II from Trichoderma reesei., Rouvinen J, Bergfors T, Teeri T, Knowles JK, Jones TA, Science. 1990 Jul 27;249(4967):380-6. PMID:2377893
Page seeded by OCA on Tue Nov 20 19:32:40 2007
