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3b2w
From Proteopedia
Contents |
Crystal structure of pyrimidine amide 11 bound to Lck
Template:ABSTRACT PUBMED 18083554
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
3B2W is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR., Deak HL, Newcomb JR, Nunes JJ, Boucher C, Cheng AC, DiMauro EF, Epstein LF, Gallant P, Hodous BL, Huang X, Lee JH, Patel VF, Schneider S, Turci SM, Zhu X, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1172-6. Epub 2007 Dec 5. PMID:18083554
Page seeded by OCA on Sun Jul 27 22:50:17 2008
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Single protein | Huang, X. | Alternative splicing | Atp-binding | Chromosomal rearrangement | Cytoplasm | Disease mutation | Host-virus interaction | Kinase domain | Lck | Lipoprotein | Membrane | Myristate | Nucleotide-binding | Palmitate | Phosphorylation | Proto-oncogene | Sh2 domain | Sh3 domain | Transferase | Tyrosine-protein kinase
