2ux8
From Proteopedia
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CRYSTAL STRUCTURE OF SPHINGOMONAS ELODEA ATCC 31461 GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE IN COMPLEX WITH GLUCOSE-1-PHOSPHATE.
Overview
Gellan gum is a widely used commercial material, available in many, different forms. Its economic importance has led to studies into the, biosynthesis of exopolysaccharide gellan gum, which is industrially, prepared in high yields using Sphingomonas elodea ATCC 31461., Glucose-1-phosphate uridylyltransferase mediates the reversible conversion, of glucose-1-phosphate and UTP into UDP-glucose and pyrophosphate, which, is a key step in the biosynthetic pathway of gellan gums. Here we present, the X-ray crystal structure of the glucose-1-phosphate uridylyltransferase, from S. elodea. The S. elodea enzyme shares strong monomeric similarity, with glucose-1-phosphate thymidylyltransferase, several structures of, which are known, although the quaternary structures of the active enzymes, are ... [(full description)]
About this Structure
2UX8 is a [Single protein] structure of sequence from [Sphingomonas elodea] with G1P as [ligand]. Active as [[1]], with EC number [2.7.7.9]. Full crystallographic information is available from [OCA].
Reference
The complex of Sphingomonas elodea ATCC 31461 glucose-1-phosphate uridylyltransferase with glucose-1-phosphate reveals a novel quaternary structure, unique among nucleoside diphosphate-sugar pyrophosphorylase members., Aragao D, Fialho AM, Marques AR, Mitchell EP, Sa-Correia I, Frazao C, J Bacteriol. 2007 Jun;189(12):4520-8. Epub 2007 Apr 13. PMID:17434970
Page seeded by OCA on Mon Oct 29 20:20:33 2007
