1py2

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Image:1py2.png

Template:STRUCTURE 1py2

Contents

Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2

Template:ABSTRACT PUBMED 14664558

Disease

Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

1PY2 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Potent small-molecule binding to a dynamic hot spot on IL-2., Thanos CD, Randal M, Wells JA, J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:14664558

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