1lis

From Proteopedia

Revision as of 18:28, 20 November 2007 by OCA (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Image:1lis.jpg

1lis, resolution 1.9Å

Drag the structure with the mouse to rotate

THE CRYSTAL STRUCTURE OF A FERTILIZATION PROTEIN

Overview

Lysin, a protein from abalone sperm, creates a hole in the envelope of the, egg, permitting the sperm to pass through the envelope and fuse with the, egg. The structure of lysin, refined at 1.9 angstroms resolution, reveals, an alpha-helical, amphipathic molecule. The surface of the protein, exhibits three features: two tracks of basic residues that span the length, of the molecule, a solvent-exposed cluster of aromatic and aliphatic amino, acids, and an extended amino-terminal hypervariable domain that is, species-specific. The structure suggests possible mechanisms of action.

About this Structure

1LIS is a Single protein structure of sequence from Haliotis rufescens. Full crystallographic information is available from OCA.

Reference

The crystal structure of lysin, a fertilization protein., Shaw A, McRee DE, Vacquier VD, Stout CD, Science. 1993 Dec 17;262(5141):1864-7. PMID:8266073

Page seeded by OCA on Tue Nov 20 20:35:30 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1lis"
Personal tools