2et2

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Image:2et2.png

Template:STRUCTURE 2et2

Crystal structure of an Asn to Ala mutant of Winged Bean Chymotrypsin Inhibitor protein

Template:ABSTRACT PUBMED 16734415

About this Structure

2ET2 is a Single protein structure of sequence from Psophocarpus tetragonolobus. Full crystallographic information is available from OCA.

Reference

Spacer Asn determines the fate of Kunitz (STI) inhibitors, as revealed by structural and biochemical studies on WCI mutants., Dasgupta J, Khamrui S, Dattagupta JK, Sen U, Biochemistry. 2006 Jun 6;45(22):6783-92. PMID:16734415

Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis., Khamrui S, Dasgupta J, Dattagupta JK, Sen U, Biochim Biophys Acta. 2005 Aug 31;1752(1):65-72. PMID:16081330

In silico mutations and molecular dynamics studies on a winged bean chymotrypsin inhibitor protein., Dasgupta J, Sen U, Dattagupta JK, Protein Eng. 2003 Jul;16(7):489-96. PMID:12915726

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