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1lsf
From Proteopedia
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THE INFLUENCE OF TEMPERATURE ON LYSOZYME CRYSTALS. STRUCTURE AND DYNAMICS OF PROTEIN AND WATER
Overview
Lysozyme structures at six different temperatures in the range 95-295 K, have been determined using X-ray crystallography at a resolution of 1.7 A., The crystals at lower temperatures had a 7.4% decrease in the unit-cell, volume. The volume change was discontinuous with the volume being near 238, 000 A(3) from 295 to 250 K and about 220 200 A(3) below 180 K. The thermal, expansion of the protein has been analyzed and shows anisotropy, which is, correlated with local atomic packing and secondary-structure elements. The, lysozyme structure at low temperature is nearly the same as that at high, temperature, with only small relative translations and rotations of, structure elements including a hinge-bending rearrangement of two domains., Because of a considerable increase of lattice disorder at low temperature, dynamical analysis of internal motion is difficult. The analysis of, structural and dynamical properties of well ordered protein-bound water, has been carried out.
About this Structure
1LSF is a Single protein structure of sequence from Gallus gallus. Active as Lysozyme, with EC number 3.2.1.17 Full crystallographic information is available from OCA.
Reference
The influence of temperature on lysozyme crystals. Structure and dynamics of protein and water., Kurinov IV, Harrison RW, Acta Crystallogr D Biol Crystallogr. 1995 Jan 1;51(Pt 1):98-109. PMID:15299341
Page seeded by OCA on Tue Nov 20 20:50:19 2007
