2gni

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Image:2gni.png

Template:STRUCTURE 2gni

PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077)

Template:ABSTRACT PUBMED 16699172

About this Structure

2GNI is a Protein complex structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity., Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D, J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172

Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity., Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D, Structure. 2003 Dec;11(12):1595-607. PMID:14656443

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