3bw5

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Template:STRUCTURE 3bw5

Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity

Template:ABSTRACT PUBMED 18291315

About this Structure

3BW5 is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1ymi. Full crystallographic information is available from OCA.

Reference

The CK2alpha/CK2beta Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules., Raaf J, Brunstein E, Issinger OG, Niefind K, Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315

Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate., Yde CW, Ermakova I, Issinger OG, Niefind K, J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:15740749

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