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1tmj
From Proteopedia
Crystal structure of E.coli apo-HPPK(W89A) at 1.45 Angstrom resolution
Template:ABSTRACT PUBMED 15952765
About this Structure
1TMJ is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Is the critical role of loop 3 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase in catalysis due to loop-3 residues arginine-84 and tryptophan-89? Site-directed mutagenesis, biochemical, and crystallographic studies., Li Y, Blaszczyk J, Wu Y, Shi G, Ji X, Yan H, Biochemistry. 2005 Jun 21;44(24):8590-9. PMID:15952765
Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents., Xiao B, Shi G, Chen X, Yan H, Ji X, Structure. 1999 May;7(5):489-96. PMID:10378268
Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution., Blaszczyk J, Shi G, Yan H, Ji X, Structure. 2000 Oct 15;8(10):1049-58. PMID:11080626
Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies., Shi G, Blaszczyk J, Ji X, Yan H, J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059
Page seeded by OCA on Mon Jul 28 11:38:41 2008
Categories: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase | Escherichia coli | Single protein | Blaszczyk, J. | Ji, X. | 6-hydroxymethyl-7,8-dihydropterin | 6-hydroxymethylpterin | Antimicrobial agent | Drug design | Folate | Hppk | Point mutant | Pyrophosphokinase | Pyrophosphoryl transfer | Structural mutagenesis | X-ray crystallography
