2ph8

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Template:STRUCTURE 2ph8

Crystal Structure of Human Beta Secretase Complexed with inhibitor

Template:ABSTRACT PUBMED 17827011

About this Structure

2PH8 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors., Moore KP, Zhu H, Rajapakse HA, McGaughey GB, Colussi D, Price EA, Sankaranarayanan S, Simon AJ, Pudvah NT, Hochman JH, Allison T, Munshi SK, Graham SL, Vacca JP, Nantermet PG, Bioorg Med Chem Lett. 2007 Nov 1;17(21):5831-5. Epub 2007 Aug 23. PMID:17827011

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