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1yz8

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Image:1yz8.png

Template:STRUCTURE 1yz8

Contents

Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome

Template:ABSTRACT PUBMED 15895993

Disease

Known disease associated with this structure: Iridogoniodysgenesis syndrome-2 OMIM:[601542], Rieger syndrome OMIM:[601542], Ring dermoid of cornea OMIM:[601542]

About this Structure

1YZ8 is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome., Chaney BA, Clark-Baldwin K, Dave V, Ma J, Rance M, Biochemistry. 2005 May 24;44(20):7497-511. PMID:15895993

Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution., Otting G, Qian YQ, Billeter M, Muller M, Affolter M, Gehring WJ, Wuthrich K, EMBO J. 1990 Oct;9(10):3085-92. PMID:1976507

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