1yc2

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Template:STRUCTURE 1yc2

Sir2Af2-NAD-ADPribose-nicotinamide

Template:ABSTRACT PUBMED 15780941

About this Structure

1YC2 is a Single protein structure of sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.

Reference

Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme., Avalos JL, Bever KM, Wolberger C, Mol Cell. 2005 Mar 18;17(6):855-68. PMID:15780941

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