2q8g

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Template:STRUCTURE 2q8g

Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545

Template:ABSTRACT PUBMED 17683942

About this Structure

2Q8G is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol., Kato M, Li J, Chuang JL, Chuang DT, Structure. 2007 Aug;15(8):992-1004. Epub 2007 Aug 2. PMID:17683942

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