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1t4u

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Revision as of 15:21, 28 July 2008 by OCA (Talk | contribs)
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Template:STRUCTURE 1t4u

Contents

Crystal Structure Analysis of a novel Oxyguanidine bound to Thrombin

Template:ABSTRACT PUBMED 15203151

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1T4U is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis., Lu T, Markotan T, Coppo F, Tomczuk B, Crysler C, Eisennagel S, Spurlino J, Gremminger L, Soll RM, Giardino EC, Bone R, Bioorg Med Chem Lett. 2004 Jul 16;14(14):3727-31. PMID:15203151

Page seeded by OCA on Mon Jul 28 18:21:08 2008

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