2phb
From Proteopedia
Contents |
An Orally Efficacious Factor Xa Inhibitor
Template:ABSTRACT PUBMED 17683371
Disease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this Structure
2PHB is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarb oxamide (PD 0348292), an orally efficacious factor Xa inhibitor., Kohrt JT, Bigge CF, Bryant JW, Casimiro-Garcia A, Chi L, Cody WL, Dahring T, Dudley DA, Filipski KJ, Haarer S, Heemstra R, Janiczek N, Narasimhan L, McClanahan T, Peterson JT, Sahasrabudhe V, Schaum R, Van Huis CA, Welch KM, Zhang E, Leadley RJ, Edmunds JJ, Chem Biol Drug Des. 2007 Aug;70(2):100-12. PMID:17683371
Page seeded by OCA on Mon Jul 28 18:48:30 2008
