1thz
From Proteopedia
Crystal Structure of Avian AICAR Transformylase in Complex with a Novel Inhibitor Identified by Virtual Ligand Screening
Template:ABSTRACT PUBMED 15355974
About this Structure
1THZ is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
Crystal structure of avian aminoimidazole-4-carboxamide ribonucleotide transformylase in complex with a novel non-folate inhibitor identified by virtual ligand screening., Xu L, Li C, Olson AJ, Wilson IA, J Biol Chem. 2004 Nov 26;279(48):50555-65. Epub 2004 Sep 7. PMID:15355974
Structural insights into the avian AICAR transformylase mechanism., Wolan DW, Greasley SE, Beardsley GP, Wilson IA, Biochemistry. 2002 Dec 31;41(52):15505-13. PMID:12501179
Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site., Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA, Biochemistry. 2003 Sep 23;42(37):10904-14. PMID:12974624
Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor., Wolan DW, Cheong CG, Greasley SE, Wilson IA, Biochemistry. 2004 Feb 10;43(5):1171-83. PMID:14756553
Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates., Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA, J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129
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