1t7i

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Template:STRUCTURE 1t7i

The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.

Template:ABSTRACT PUBMED 15771427

About this Structure

1T7I is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor., Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB, J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427

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