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2hr7

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Revision as of 18:04, 28 July 2008 by OCA (Talk | contribs)
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Image:2hr7.png

Template:STRUCTURE 2hr7

Contents

Insulin receptor (domains 1-3)

Template:ABSTRACT PUBMED 16894147

Disease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]

About this Structure

2HR7 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity., Lou M, Garrett TP, McKern NM, Hoyne PA, Epa VC, Bentley JD, Lovrecz GO, Cosgrove LJ, Frenkel MJ, Ward CW, Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12429-34. Epub 2006 Aug 7. PMID:16894147

Page seeded by OCA on Mon Jul 28 21:04:10 2008

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