1z3n
From Proteopedia
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
Template:ABSTRACT PUBMED 15857120
About this Structure
1Z3N is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications., Van Zandt MC, Jones ML, Gunn DE, Geraci LS, Jones JH, Sawicki DR, Sredy J, Jacot JL, Dicioccio AT, Petrova T, Mitschler A, Podjarny AD, J Med Chem. 2005 May 5;48(9):3141-52. PMID:15857120
Page seeded by OCA on Mon Jul 28 21:59:06 2008
