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2iws

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Image:2iws.png

Template:STRUCTURE 2iws

RADICICOL ANALOGUES BOUND TO THE ATP SITE OF HSP90

Template:ABSTRACT PUBMED 17114002

About this Structure

2IWS is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol., Proisy N, Sharp SY, Boxall K, Connelly S, Roe SM, Prodromou C, Slawin AM, Pearl LH, Workman P, Moody CJ, Chem Biol. 2006 Nov;13(11):1203-15. PMID:17114002

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