3bgl

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Image:3bgl.png

Template:STRUCTURE 3bgl

Contents

Hepatoselectivity of Statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Template:ABSTRACT PUBMED 18155906

Disease

Known disease associated with this structure: Statins, attenuated cholesterol lowering by OMIM:[142910]

About this Structure

3BGL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors., Park WK, Kennedy RM, Larsen SD, Miller S, Roth BD, Song Y, Steinbaugh BA, Sun K, Tait BD, Kowala MC, Trivedi BK, Auerbach B, Askew V, Dillon L, Hanselman JC, Lin Z, Lu GH, Robertson A, Sekerke C, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1151-6. Epub 2007 Dec 5. PMID:18155906

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