2v07

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spinqualitylabelsall models 2v07, resolution 1.602Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

STRUCTURE OF THE ARABIDOPSIS THALIANA CYTOCHROME C6A V52Q VARIANT

Overview

Cytochrome c6A is a unique dithio-cytochrome of green algae and plants. It, has a very similar core structure to that of bacterial and algal, cytochromes c6 but is unable to fulfill the same function of transferring, electrons from cytochrome f to photosystem I. A key feature is that its, heme midpoint potential is more than 200 mV below that of cytochrome c6, despite having His and Met as axial heme-iron ligands. To identify the, molecular origins of the difference in potential, the structure of, cytochrome c6 from the cyanobacterium Phormidium laminosum has been, determined by X-ray crystallography and compared with the known structure, of cytochrome c6A. One salient difference of the heme pockets is that a, highly conserved Gln (Q51) in cytochrome c6 is replaced by Val (V52) in, c6A. ... [(full description)]

About this Structure

2V07 is a [Single protein] structure of sequence from [Arabidopsis thaliana] with HEM as [ligand]. Full crystallographic information is available from [OCA].

Reference

Modulation of Heme Redox Potential in the Cytochrome c(6) Family., Worrall JA, Schlarb-Ridley BG, Reda T, Marcaida MJ, Moorlen RJ, Wastl J, Hirst J, Bendall DS, Luisi BF, Howe CJ, J Am Chem Soc. 2007 Aug 1;129(30):9468-75. Epub 2007 Jul 11. PMID:17625855

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