2jmn

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Image:2jmn.png

Template:STRUCTURE 2jmn

Contents

NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures

Template:ABSTRACT PUBMED 8951384

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2JMN is a Protein complex structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entries and 1vks. Full experimental information is available from OCA.

Reference

Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue., Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA, J Mol Biol. 1996 Nov 29;264(2):390-403. PMID:8951384

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