2af9

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Template:STRUCTURE 2af9

Contents

Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine

Template:ABSTRACT PUBMED 16216074

Disease

Known disease associated with this structure: GM2-gangliosidosis, AB variant OMIM:[272750]

About this Structure

2AF9 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity., Wright CS, Mi LZ, Lee S, Rastinejad F, Biochemistry. 2005 Oct 18;44(41):13510-21. PMID:16216074

Crystal structure of human GM2-activator protein with a novel beta-cup topology., Wright CS, Li SC, Rastinejad F, J Mol Biol. 2000 Dec 1;304(3):411-22. PMID:11090283

Structural analysis of lipid complexes of GM2-activator protein., Wright CS, Zhao Q, Rastinejad F, J Mol Biol. 2003 Aug 22;331(4):951-64. PMID:12909021

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