3bu6
From Proteopedia
Contents |
Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB phosphopeptide
Template:ABSTRACT PUBMED 18278056
Disease
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]
About this Structure
3BU6 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2., Wu J, Tseng YD, Xu CF, Neubert TA, White MF, Hubbard SR, Nat Struct Mol Biol. 2008 Mar;15(3):251-8. Epub 2008 Feb 17. PMID:18278056
Page seeded by OCA on Tue Jul 29 07:28:05 2008
Categories: Homo sapiens | Protein complex | Receptor protein-tyrosine kinase | Hubbard, S R. | Wu, J. | Alternative splicing | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Insulin receptor | Ir | Irk | Irs-2 | Kinase | Krlb | Membrane | Nucleotide-binding | Phosphopeptide | Phosphoprotein | Polymorphism | Transducer | Transferase | Transmembrane | Tyrosine-protein kinase
