2zm3
From Proteopedia
Contents |
Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor
Template:ABSTRACT PUBMED 18501599
Disease
Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147370]
About this Structure
2ZM3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment., Mayer SC, Banker AL, Boschelli F, Di L, Johnson M, Kenny CH, Krishnamurthy G, Kutterer K, Moy F, Petusky S, Ravi M, Tkach D, Tsou HR, Xu W, Bioorg Med Chem Lett. 2008 Jun 15;18(12):3641-5. Epub 2008 Apr 25. PMID:18501599
Page seeded by OCA on Tue Jul 29 08:40:15 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Boschelli, F. | Dwyer, B. | Johnson, M. | Mayer, S C. | Xu, W. | Atp-binding | Cleavage on pair of basic residue | Disease mutation | Glycoprotein | Igfr | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Protein-inhibitor complex | Receptor | Transferase | Transmembrane | Tyrosine kinase | Tyrosine-protein kinase
