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1q7e

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1q7e, resolution 1.60Å

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Crystal Structure of YfdW protein from E. coli

Overview

Crystal structures are reported for free and coenzyme A (CoA) bound forms, of the YfdW protein from Escherichia coli, a representative type III CoA, transferase. The structures reveal a two-domain protomer with interdomain, connections forming a ring-like structure with a large central hole. Two, protomers associate to form a highly intertwined dimer in which the hole, of each ring is filled by the partner molecule. Each protomer binds a, single CoA molecule and these CoA-binding sites are distant from one, another in the dimer.

About this Structure

1Q7E is a Single protein structure of sequence from Escherichia coli with MET and MPD as ligands. Full crystallographic information is available from OCA.

Reference

Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:14993676

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