2z8c
From Proteopedia
Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid
Disease
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670], Coronary artery disease, susceptibility to OMIM:[147545], Diabetes mellitus, noninsulin-dependent OMIM:[147545]
About this Structure
2Z8C is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Aug 13 14:28:02 2008
Categories: Homo sapiens | Protein complex | Receptor protein-tyrosine kinase | Katayama, N. | Kurihara, H. | Alternative splicing | Atp-binding | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Transducer | Transferase | Transmembrane | Tyrosine-protein kinase
