2r2m
From Proteopedia
Contents |
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Template:ABSTRACT PUBMED 17889527
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
2R2M is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527
Page seeded by OCA on Wed Aug 27 11:08:24 2008
Categories: Hirudo medicinalis | Homo sapiens | Protein complex | Thrombin | Spurlino, J. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Polymorphism | Protease | Protease inhibitor | Secreted | Serine protease | Serine protease inhibitor | Sulfation | Zymogen