3dbs
From Proteopedia
Structure of PI3K gamma in complex with GDC0941
Template:ABSTRACT PUBMED 18754654
About this Structure
3DBS is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin -4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer ., Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ, J Med Chem. 2008 Sep 25;51(18):5522-32. PMID:18754654
Page seeded by OCA on Wed Oct 8 09:05:10 2008
