This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3e64
From Proteopedia
Fragment based discovery of JAK-2 inhibitors
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
3E64 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Oct 15 15:27:54 2008
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Single protein | Antonysamy, S S. | Atp-binding | Chromosomal rearrangement | Disease mutation | Drug discovery | Fragment based | Jak2 | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
