1t99
From Proteopedia
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r106g kdo8ps without substrates
Overview
A new software suite, called Crystallography & NMR System (CNS), has been, developed for macromolecular structure determination by X-ray, crystallography or solution nuclear magnetic resonance (NMR) spectroscopy., In contrast to existing structure-determination programs, the architecture, of CNS is highly flexible, allowing for extension to other, structure-determination methods, such as electron microscopy and, solid-state NMR spectroscopy. CNS has a hierarchical structure: a, high-level hypertext markup language (HTML) user interface, task-oriented, user input files, module files, a symbolic structure-determination, language (CNS language), and low-level source code. Each layer is, accessible to the user. The novice user may just use the HTML interface, while the more advanced user may use any of the other layers. The source, code will be distributed, thus source-code modification is possible. The, CNS language is sufficiently powerful and flexible that many new, algorithms can be easily implemented in the CNS language without changes, to the source code. The CNS language allows the user to perform operations, on data structures, such as structure factors, electron-density maps, and, atomic properties. The power of the CNS language has been demonstrated by, the implementation of a comprehensive set of crystallographic procedures, for phasing, density modification and refinement. User-friendly, task-oriented input files are available for nearly all aspects of, macromolecular structure determination by X-ray crystallography and, solution NMR.
About this Structure
1T99 is a Single protein structure of sequence from Aquifex aeolicus with PO4 and CD as ligands. Active as 3-deoxy-8-phosphooctulonate synthase, with EC number 2.5.1.55 Full crystallographic information is available from OCA.
Reference
Crystallography & NMR system: A new software suite for macromolecular structure determination., Brunger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL, Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):905-21. PMID:9757107
Page seeded by OCA on Wed Nov 21 03:05:38 2007
