3d0e
From Proteopedia
Contents |
Crystal structure of human Akt2 in complex with GSK690693
Template:ABSTRACT PUBMED 18800763
Disease
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]
About this Structure
3D0E is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]o xy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase., Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R, J Med Chem. 2008 Sep 25;51(18):5663-79. PMID:18800763
Page seeded by OCA on Wed Oct 22 10:44:37 2008
