3e8r
From Proteopedia
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3E8R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:18835710
Page seeded by OCA on Wed Oct 22 10:51:38 2008
Categories: ADAM 17 endopeptidase | Homo sapiens | Single protein | Orth, P. | Alternative splicing | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Tace adam17 zn-endopeptidase | Transmembrane | Zinc | Zymogen
