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3e3w

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Template:STRUCTURE 3e3w

Crystal structure of human beta secretase complexed with spiropiperdine imidohydantoin inhibitor.

Template:ABSTRACT PUBMED 18811140

About this Structure

3E3W is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase., Barrow JC, Stauffer SR, Rittle KE, Ngo PL, Yang Z, Selnick HG, Graham SL, Munshi S, McGaughey GB, Holloway MK, Simon AJ, Price EA, Sankaranarayanan S, Colussi D, Tugusheva K, Lai MT, Espeseth AS, Xu M, Huang Q, Wolfe A, Pietrak B, Zuck P, Levorse DA, Hazuda D, Vacca JP, J Med Chem. 2008 Oct 23;51(20):6259-62. Epub 2008 Sep 24. PMID:18811140

Page seeded by OCA on Wed Oct 29 11:00:37 2008

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