3dxj

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Image:3dxj.png

Template:STRUCTURE 3dxj

Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin

Template:ABSTRACT PUBMED 18957204

About this Structure

3DXJ is a 12 chains structure of sequences from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

Reference

The RNA polymerase "switch region" is a target for inhibitors., Mukhopadhyay J, Das K, Ismail S, Koppstein D, Jang M, Hudson B, Sarafianos S, Tuske S, Patel J, Jansen R, Irschik H, Arnold E, Ebright RH, Cell. 2008 Oct 17;135(2):295-307. PMID:18957204

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