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From Proteopedia
Hemostasis is a control mechanism in the circulatory system that responsible for the stoppage of bleeding by changing the fluid state of the blood into solid state. Hemostasis as two stages: primary homeostasis includes vascular contraction, platelet adhesion and formation of a soft aggregate plug. Primary Hemostasis starts very quickly after the injury. However it is temporary and local contraction that should be stabilized by the secondary hemostasis.
Secondary hemostasis is a complex system resulting fibrin formation as an output of the interaction between coagulation factors. Coagulation factors are serine proteases that forms coagulation cascade. It can be initiated via two different pathways: intrinsic and extrinsic.
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