3bg8

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Template:STRUCTURE 3bg8

Contents

Crystal structure of Factor XIa in complex with Clavatadine A

Template:ABSTRACT PUBMED 18510371

Disease

Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]

About this Structure

3BG8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Clavatadine A, a natural product with selective recognition and irreversible inhibition of factor XIa., Buchanan MS, Carroll AR, Wessling D, Jobling M, Avery VM, Davis RA, Feng Y, Xue Y, Oster L, Fex T, Deinum J, Hooper JN, Quinn RJ, J Med Chem. 2008 Jun 26;51(12):3583-7. PMID:18510371

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