Proteopedia:Main page develop
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Welcome to Proteopedia,
The free, collaborative 3D encyclopedia
of proteins & other molecules
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The anti-Alzheimer's drug E2020 (marketed as Aricept®) is an inhibitor that binds acetylcholinesterase (AChE) with high affinity. The X-ray structure of the E2020-AChE (AChE from Torpedo california) complex shows that E2020 has a along the active-site gorge, extending from the anionic subsite () of the active site, at the bottom, to the peripheral anionic site (), at the top, via aromatic stacking interactions with conserved aromatic acid residues. E2020 does not, however, interact directly with either the catalytic triad or the 'oxyanion hole' but only . Read more at 1eve... |
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Want to contribute?
Green links are easy to make! We encourage you to edit pages freely and to add new pages.
You will need a user account in order to edit or add pages. Please go ahead and request a user account.
If you have any questions, you can email 
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These resources may help you familiarize yourself with the editing process. Trust us, the editing process is very simple: All text is edited the same way that Wikipedia is edited, so it must be easy! And all scenes (green links) are created using our user-friendly Scene authoring tools. Of course it helps to familiarize yourself with the site and how to go about editing, so check out these resources:
- The Proteopedia Video Guide is a narrated video guide that serves both as a starting point as well as a reference.
- The Editing Help Page.
- The help page for the Scene authoring tools.
- Proteopedia:Policies and the Proteopedia: Email list
What Can Proteopedia Do For Me?
- Scientists and Students: a reference resource for understanding protein 3D structure-function relationships. Example: Acetylcholinesterase bound to Aricept, an anti-Alzheimer's drug.
- Educators: develop tutorials or molecular scenes to project during lectures, or for student use. Examples: Teaching Scenes, Tutorials, and Educators' Pages. Assign students to construct pages in Proteopedia for class projects or reports: see Student Projects. See also Teaching Strategies Using Proteopedia.
You may protect your teaching pages from unwanted editing by others -- see Help:Protected Pages.
- Structural Researchers: create supplementary materials for your journal publications, and pages about your research team or institute, highlighting structures you have researched. For examples, see Research Groups.
You may protect such pages from unwanted editing by others -- see Help:Protected Pages.
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What can Proteopedia do for me?
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Scientists and Students
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Educators
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Structural researchers
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You may protect your teaching pages from unwanted editing by others -- see Help:Protected Pages. |
You may protect such pages from unwanted editing by others -- see Help:Protected Pages. |
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