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3dm6
From Proteopedia
Beta-secretase 1 complexed with statine-based inhibitor
Template:ABSTRACT PUBMED 18842420
About this Structure
3DM6 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues., Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B, Bioorg Med Chem. 2008 Nov 1;16(21):9471-86. Epub 2008 Sep 19. PMID:18842420
Page seeded by OCA on Wed Dec 17 13:43:10 2008
Categories: Homo sapiens | Memapsin 2 | Borkakoti, N. | Lindberg, J. | Nystrom, S. | Alternative splicing | Aspartyl protease | Bace | Beta-secretase | Glycoprotein | Hydrolase | Inhibitor | Membrane | Protease | Statine | Transmembrane | Zymogen
