2vx1

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Template:STRUCTURE 2vx1

EPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18434142

About this Structure

2VX1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines., Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ, Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142

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