2prm

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Template:STRUCTURE 2prm

The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site

Template:ABSTRACT PUBMED 18672895

About this Structure

2PRM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites., Walse B, Dufe VT, Svensson B, Fritzson I, Dahlberg L, Khairoullina A, Wellmar U, Al-Karadaghi S, Biochemistry. 2008 Aug 26;47(34):8929-36. Epub 2008 Aug 2. PMID:18672895

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