2w2p

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Template:STRUCTURE 2w2p

PCSK9-DELTAC D374A MUTANT BOUND TO WT EGF-A OF LDLR

Template:ABSTRACT PUBMED 19001363

About this Structure

2W2P is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structural and biochemical characterization of the wild type PCSK9/EGF-AB complex and natural FH mutants., Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfi A, J Biol Chem. 2008 Nov 10. PMID:19001363

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